Bethel Presbyterian Church in the Fayette County seat of West Union was officially organized in June 1867 with 12 charter members. The congregation first met in an old church facility and then the Fayette County Courthouse before a new brick building was constructed and dedicated in 1872. The first church was remodeled in 1893, but plans for an addition were interrupted when the building was destroyed by fire on February 11, 1922.

Prompt action was taken to construct a new church on the site of the old one, with the cornerstone laid on September 17, 1922 and dedication services held the following year. A basement was added in 1951, while an education wing was added (in the lighter brick) in 1961.